It’s finally happening. The first new class of antidepressant medication in 30 years. On February 12, the FDA advisory committee gave it’s approval to esketamine to be marketed under the trade name SpravatoTM by Janssen Pharmaceutical Companies of Johnson & Johnson for TRD and for MDD with an imminent risk of suicide.1

Here is a summary of what you need to know:

  1. Johnson & Johnson. FDA Advisory Committee Recommends Approval of SPRAVATOTM (esketamine) Nasal Spray CIII for Adults with Treatment-Resistant Depression. accessed February 25, 2019.
  2. Williams NR, Heifets BD, Blasey C, et al. Attenuation of antidepressant effects of ketamine by opioid receptor antagonism. Am J Psych. 2018;175(12):1205-1215.

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